Manipulation loading system is a crucial component in flight simulators, providing realistic force feedback to the pilot during training. At the heart of this system lies the spherical actuator, a device capable of generating multi-directional forces within a spherical workspace. To ensure accurate and responsive force reproduction, this paper propose meticulous structural optimization and precise control mechanisms for manipulation loading system with spherical actuator. Structural optimization enhances the actuator's performance, while control strategies realizes smooth and accurate force delivery. These advancements are necessary to fulfill the demanding requirements of modern flight simulators, providing pilots with a highly realistic and immersive training experience.