A 55-year-old female presents with a left iliac fossa mass of a few months in duration. An MRI shows a pelvic mass (Fig. 1a). No other evidence of distant metastasis was found in a staging CT chest/abdomen/pelvis. Ultrasound guided biopsy of the mass returned as a spindle and round cell tumour that was positive for CD34, CD99 and had strong nuclear positivity for STAT6. EWSR-1 break-apart FISH was negative. Diagnosis was favouring that of solitary fibrous tumour. The mass of deemed unresectable and she underwent palliative chemotherapy with doxorubicin and dacarbazine. However, best response was that of stable disease.

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Solitary Fibrous Tumour

  • Victor K. Lee,
  • Tien Jin Tan,
  • Alison Cheah,
  • Fiona Maclean,
  • Esther Wei Yin Chang

摘要

A 55-year-old female presents with a left iliac fossa mass of a few months in duration. An MRI shows a pelvic mass (Fig. 1a). No other evidence of distant metastasis was found in a staging CT chest/abdomen/pelvis. Ultrasound guided biopsy of the mass returned as a spindle and round cell tumour that was positive for CD34, CD99 and had strong nuclear positivity for STAT6. EWSR-1 break-apart FISH was negative. Diagnosis was favouring that of solitary fibrous tumour. The mass of deemed unresectable and she underwent palliative chemotherapy with doxorubicin and dacarbazine. However, best response was that of stable disease.