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Chondrosarcoma is the second most common primary malignant bone tumor, characterized by the production of a cartilaginous matrix. It typically affects the pelvis, proximal femur, and ribs, with a higher incidence in middle-aged and older adults. Imaging plays a crucial role in diagnosis, with radiographs, CT, and MRI aiding in differentiation from benign cartilaginous lesions. Histological grading is essential for prognosis, as higher-grade tumors exhibit more aggressive behavior and increased metastatic potential. Treatment is primarily surgical, as conventional chondrosarcoma is resistant to chemotherapy and radiotherapy.

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Chondrosarcoma

  • 章节

  • 发表日期：

    2025年

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  • James Thomas Patrick Decourcy Hallinan,
  • Mai Adnan Banjar,
  • Eugene Guerrero Odoño,
  • Victor K. Lee,
  • Matilda Xin Wei Lee,
  • Suraya Zainul-Abidin,
  • Henry Soeharno

摘要

Chondrosarcoma is the second most common primary malignant bone tumor, characterized by the production of a cartilaginous matrix. It typically affects the pelvis, proximal femur, and ribs, with a higher incidence in middle-aged and older adults. Imaging plays a crucial role in diagnosis, with radiographs, CT, and MRI aiding in differentiation from benign cartilaginous lesions. Histological grading is essential for prognosis, as higher-grade tumors exhibit more aggressive behavior and increased metastatic potential. Treatment is primarily surgical, as conventional chondrosarcoma is resistant to chemotherapy and radiotherapy.