Metal-organic frameworks (MOFs) have emerged as a promising class of materials for the detection of toxic liquids due to their unique properties. MOFs are composed of metal ions or clusters coordinated to organic molecules or ligands to form a porous three-dimensional network with high surface area and tunable pore sizes. The selective binding sites of MOFs can detect and differentiate between various liquids accurately. MOF-based liquid sensors can detect low concentrations of toxic liquids in the environment, enabling rapid response to leaks or other hazards. However, the sensitivity, selectivity, and stability of MOF-based liquid sensors need to be improved to ensure that they can detect and differentiate between various liquids accurately and reliably. Researchers are exploring new MOF materials with enhanced liquid sensing properties, including higher sensitivity, selectivity, and stability. They are also investigating new methods for MOF synthesis and liquid sensor fabrication to optimize sensor performance. Integration with other sensing technologies, such as optical or electrical sensors, is a promising approach to enhance the performance and accuracy of liquid detection. In conclusion, MOF-based liquid sensors hold great promise for the detection of toxic liquids, but further research and development is needed to overcome several challenges and to optimize their performance for real-world applications.