The transmission of COVID-19 has become a global pandemic in 2020. Communities and nations tried their best to cope with this virus, including indigenous people in Indonesia, who are considered more vulnerable than others. However, some indigenous people have only recorded a minimum of zero cases and have successfully protected their members from the virus. This article describes and analyses the responses of some indigenous people in Indonesia during the COVID-19 pandemic. We found that indigenous people can apply the local lockdown effectively and have some local knowledge when responding to the global pandemic. One of which is besesandingon to keep a distance from the seriously ill patients in the community of Orang Rimba in the Province of Jambi. However, in order to transfer the sense of crisis, the activists and people who care need a specific strategy to translate the situation to the indigenous people in Indonesia. Therefore, we are concerned that the government needs to learn from the indigenous people's local wisdom and create a specific regulation on how to transmit such an urgent situation but still be understood by the indigenous people.