Campylobacter species are ubiquitous pathogens in the livestock industry, posing significant challenges to food safety and animal health. Campylobacter infection ranks among the most prevalent causes of foodborne gastroenteritis worldwide. Given its presence as a commensal bacterium in the intestines of food-producing animals, Campylobacter seamlessly infiltrates the food chain. Consequently, humans are at risk of acquiring the infection through the ingestion of contaminated food items. A pivotal aspect influencing their persistence and dissemination within livestock environments is their adeptness at forming biofilms. This review encapsulates the attributes of Campylobacter biofilms, focuses both biological and nonbiological elements impacting their formation, and examines strategies for their control. This review offers a deep molecular insight into the architecture of Campylobacter biofilms within the livestock context, emphasizing the unique molecular components and mechanisms driving their formation, stability, and resistance to environmental stressors. The role of livestock-associated factors, including feed, water sources, and farm infrastructure, in modulating Campylobacter biofilm dynamics will also be elucidated. By integrating a livestock-centric perspective, this review underscores the intricate molecular interplay governing Campylobacter biofilm formation and its profound implications for livestock health, farm hygiene, and human health outcomes. The insights gleaned pave the way for targeted interventions and management strategies tailored to mitigate Campylobacter-associated risks within livestock production systems.