Taking the 480 red tourism resources in Guangdong Province as the research object, using the method of combining spatial analysis and SWOT analysis, we discuss the spatial distribution, influencing factors and development and utilization status of red tourism resources in Guangdong Province. Our research found that the spatial distribution of red tourism resources in Guangdong Province is in the shape of “one focus and multiple points”. The overall spatial distribution is negatively correlated, and the distribution difference is significant. The overall spatial correlation degree is low while the local spatial correlation degree is high. The spatial distribution characteristics of red tourism resources in Guangdong Province are mainly affected by historical, economic and policy factors. The current situation of the development and utilization of red tourism resources in Guangdong Province is the coexistence of opportunities from the tourism market and policies and challenges from market competition. Finally, we put forward some suggestions for the development and utilization of red tourism resources in Guangdong Province.