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Orlistat is a USFDA-approved weight loss drug that can be used for long-term. Orlistat is a gastrointestinal lipase inhibitor that selectively inhibits the gastric & pancreatic lipases, which leads to decreased fat absorption and increased fecal fat excretion. This mechanism of action helps in weight loss and reducing visceral fat [1].

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Orlistat: A Gastrointestinal Lipase Inhibitor

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  • 发表日期：

    2025年

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  • Shilpa Chugh Garcha,
  • Sanjay Kalra

摘要

Orlistat is a USFDA-approved weight loss drug that can be used for long-term. Orlistat is a gastrointestinal lipase inhibitor that selectively inhibits the gastric & pancreatic lipases, which leads to decreased fat absorption and increased fecal fat excretion. This mechanism of action helps in weight loss and reducing visceral fat [1].