Precipitation non-uniformity is an important feature of regional geography and development, based on the day-by-day precipitation data from 17 air stations using linear trend study, Mann-Kendall mutation test, precipitation concentration (PCD) and precipitation concentration period (PCP) indicators to analyze the spatial and temporal characteristics of precipitation non-uniformity in this Qilian Mountains from 1960 to 2017. The results show that; the temporal distribution, precipitation is increasing trend and mainly concentrated in July, PCD overall value close to 1, PCP interannual change is not obvious; spatial distribution, Qilian Mountains average annual precipitation spatial distribution there are obvious differences, the overall presentation of the southeast more than the northwest, the monthly precipitation spatial distribution is basically the same, the total amount of precipitation south slope is greater than the north slope, and PCD and PCP spatial basically the same; the M-K mutation The M-K mutation test concluded that the precipitation headquarters in Qilian Mountains showed an increasing trend, the mutation occurred before and after 2002, and the upward trend was significant after 2006; there was no significant difference between the PCD and PCP in the Qilian Mountains in the watery year and the watery year, and the fluctuation of the PCD and the PCP had a significant effect on the annual precipitation.