Diagrid systems possess the key characteristic of substantially decreasing the quantity of columns typically used in building projects. A reduced number of columns leads to a floor plan that is more spacious and flexible, which is a crucial factor in contemporary architectural design, particularly for tall commercial and residential buildings. This research study examines the analysis and design of diagrid systems for tall buildings, specifically focused on storey heights ranging from 30 to 66 floors. An essential component of this study involves investigating several height-to-base (h/b) ratios, specifically 2.58, 3.1, 3.616, 4.13, 4.65, 5.16, and 5.68, as specified by the Indian Standard Code 800-2007. This code functions as a blueprint for the architectural layout of steel structures in India, guaranteeing that the diagrid systems comply with national safety and construction regulations. The findings of this study are extensive, including a range of structural factors. The axial force of columns, shear force of columns, and axial force of diagonals are thoroughly contrasted and analysed. Furthermore, the study focuses specifically on deflection, which is a crucial aspect in ensuring the structural stability and safety of tall buildings. Through the analysis of these factors, the study offers valuable perspectives on the efficacy of various diagrid layouts and their influence on building performance. In summary, this paper makes a substantial contribution to the field of architectural engineering by providing a comprehensive analysis of diagrid systems in high-rise buildings. The findings not only improve the diagrid system design but also impact the design of skyscrapers.