Progressive collapse is a significant issue in the field of structural engineering. It refers to the chain reaction of localized structural failure, which results in the subsequent destruction of nearby elements. This phenomenon becomes especially apparent when vertical load-bearing elements, such as columns, give way to unintentional loads, whether caused by human-made accidents or natural calamities. The current study explores the complexities of progressive collapse by doing a thorough analysis of a building utilizing the advanced FEM software. The main objective of this research is to model and assess the progressive collapse of a structure through the selective removal of columns. Multiple scenarios involving the removal of columns are analysed in order to gain a thorough understanding of the vulnerabilities and consequences connected with these changes to the structure. The Demand Capacity Ratio (DCR) of beams is computed in accordance with the rules set by the General Services Administration (GSA) for each specific scenario. This essential measurement acts as a pivotal signal in evaluating the stability of a structure against increasing collapse. The computed DCR values offer valuable information about the structural robustness in various loading scenarios and allow for a precise assessment of the building’s ability to endure localized breakdowns. The study highlights the importance of comprehending gradual collapse in relation to seismic events. This research enhances the ongoing discussion on structural integrity by providing a thorough investigation of progressive collapse using advanced computer analysis. It emphasizes the importance of designing structures that demonstrate resilience against unexpected events.