As a typical complex system engineering covering aerodynamics, structure, propulsion, control, and other disciplines, including a large number of design variables, performance state variables, and constraint equations, as well as the mutual influence between different disciplines or subsystems, aircraft design is characterized with high complexity in the optimization of system design (Li in The general design of modern aircraft. Northwestern Polytechnic University Press, Xi’an, (2001) [1]; Gu and Sishi in Aircraft general design. Beihang University Press, Beijing, (2002) [2]; Li in Aircraft general design. Northwestern Polytechnic University Press, Xi’an, (2005) [3]; Zheng in Aircraft general design. Beihang University Press, Beijing, (2019) [4]; Ouyang in research on the key technologies and applications of uncetainty-based multidisciplinary design optimization for flight vehicles. National University of Defense Technology, Changsha, (2013) [5]). American Institute of Aeronautics and Astronautics (AIAA) summarizes the shortcomings of the traditional aircraft design approach as “shortage of conceptual design phases, poor discipline distribution, inability to take full advantage of design freedom in the conceptual phase to improve design quality, and difficulty in integrating multiple disciplines to achieve integrated optimization and balanced design.