Buried pipelines, used to transport the oil and natural gas, are more vulnerable to failure due to earthquake (EQ) induced permanent ground deformation (PGD), such as fault dislocation, slope instability, lateral spreading, landslides, and liquefaction-induced displacement. This ground deformation induces moderate to large strains into the ground resulting in the catastrophic damage to the pipelines. Therefore, the estimation of response of these pipelines, prior to the installation, is significantly important especially when it pass through the moderate to severe seismic zones like North Eastern (NE) region of India. Recently, in Silchar city of NE region, a steel pipeline has been lay down to supply gases across city of Assam state. This study aims to investigate the response of buried pipelines, of Silchar city, using finite element-based software ABAQUS at different fault displacements ranging from 20 to 80 cm. The results obtained from analysis indicate that an increase in the amplitude of fault displacement from 20 to 80 cm, the amplitude of strain induced on the pipeline is increased in the order of 187%–347%; whereas, the stresses increased in the order of 24–72%. The maximum value of stress was found to be increased with an increase in fault displacement from 20 to 40 cm; however, further an increase in fault displacement from 40 to 80 cm, for 6-inch pipe, reflects almost asymptotic behavior.