Suicide is a challenge all societies and nations face. Therefore, prevention of suicide is a significant public health concern across the globe. Training individuals to act as gatekeepers to suicide prevention is a practical step to prevent suicide. Gatekeepers identify people who may be at risk of suicide and accordingly intervene. With brief training, anybody in society can play a gatekeeper’s role. This chapter outlines gatekeepers’ training as a preventive strategy for suicide, explores different models of gatekeeper training, and evaluates the efficacy of gatekeepers’ programs as a suicide prevention strategy.