This chapter assesses the seismic hazard parameters for the Itanagar region, located in the state of Arunachal Pradesh, India. Itanagar, the state capital, sits at 27.1°N latitude and 93.62°E longitude within the Himalayan Fold Thrust (HFT) belt. The area is classified as seismic zone-V, one of the highest levels of seismic risk worldwide. The study area is located near active seismic sources, with a history of significant earthquakes such as the 1950 Great Assam Earthquake (Mw 8.6), the 1897 Great Shillong Earthquake (Mw 8.7), and the 1869 Great Cachar Earthquake (Mw 8.6). Recent occurrences of smaller magnitude earthquakes suggest that large seismic events may reoccur. Rapid urbanization and population growth have further heightened the region's vulnerability to seismic hazards. An extensive earthquake catalog has been compiled using data from various sources within a 300 km radius around Itanagar, covering the period from 1900 to 2024. The data have been standardized to a unified moment magnitude scale, and declustering has been carried out to distinguish dependent seismic events from mainshocks. Additionally, a completeness analysis of the earthquake catalog was conducted using the cumulative visual inspection (CUVI) method, which involves plotting the cumulative number of events per year against the time period for various magnitude ranges. The final catalog consists of 841 events after the homogenization, declustering, as well as the completeness study of the earthquake events. A seismicity map for Itanagar has been prepared that shows the locations of seismic events in the region, earthquake magnitude, and other parameters. The map can be used to estimate the risk of earthquake occurrence in the region. It can also be used to identify areas that need seismic hazard mitigation measures and seismic-resistant construction. The catalog has been divided into several magnitude classes, 3 ≤ Mw ≤ 3.9, 4 ≤ Mw ≤ 4.9, 5 ≤ Mw ≤ 5.9, 6 ≤ Mw ≤ 6.9, and 7 ≤ Mw ≤ 7.9. The estimated value of the seismic hazard variable ‘b’ was determined to be 1.08(±0.05) for complete data by using Gutenberg–Richter (G-R) relationship. Furthermore, a comparison of the ‘b’ values derived from this study with those from previous research has been presented for illustration. The ‘b’ value, which indicates the frequency of smaller versus larger earthquakes, helps in evaluating the likelihood of seismic events occurring over time, allowing urban planners to develop strategies for risk reduction and emergency preparedness. The study fills a critical gap by focusing on the Itanagar region, which has not been extensively studied for seismic hazard parameters.