A high-resolution noise free medical image is an essential requirement for accurate disease detection. Medical image processing and analysis techniques have become utmost important in recent decades as a supplementary competence for medical professionals in the fields of diagnosis and prevention. Obtaining high-quality images without any interference is a crucial requirement for effectively managing therapeutic images. Medical images may contain many types of noises for involvement of simultaneous operation of multiple equipment involved in data capturing and transmission. Various filters have been suggested for eliminating different types of noises, each having its own merits and drawbacks depending on its capabilities and projected benefits. Our research depicts a technique for removing noises from medical images using a hybrid filtering approach based on ensemble adaptive mean filtering and Block-matching-3D filtering. The proposed methodologies specifically aim to reduce the speckle noise in brain MRI images obtained from ultrasonic therapy by employing hybrid filtering techniques. This proposed hybrid filtering algorithms integrate the most effective aspects of high-performance filters to achieve a de-noised image that retains fine details, edges, and textures. The statistical performance measurement metrics like Root Mean Square Error (RMSE), Peak Signal-to-Noise Ratio (PSNR) are employed to evaluate the improved visual quality of the images. The results indicate that our proposed hybrid filtering technique functioning efficiently and provide better quality de-noised image compare with other existing de-noising techniques.