The biosphere represents an intricate and colorful ultra macroscopic system emerging from the chemical world and obeys basic physical and chemical laws. Chemical kinetics is an effective tool for studying the dynamic behavior of near-equilibrium chemical systems. Therefore, as the basic structural elements of the interconnection between cells and the external environment, the functional cycle of MPs can be described by chemical kinetic theory. This chapter introduces basic concepts of chemical kinetics related to the structural dynamics of MPs and attempts to address the following questions: How do MPs increase and regulate the rate of trans-membrane material transport, energy conversion, and information conduction? Where does the driving energy come from, and how can it be effectively used? How do we quantitatively or semiquantitatively describe the energy coupling process under the constraints of the laws of thermodynamics? How can concentration gradients be used to drive functional cycles of MPs? We will discuss methods for quantifying triple jumps in enzymes, the relationship between ligand affinity differences and energy coupling, free-energy landscapes, and common features of bistable models. The content of this chapter will lay the foundation to understand the discussions in the following chapters (the primary objective of this book is to introduce dynamic concepts in the investigation of MP structure, avoiding the detailed derivation of complex physics equations. In this chapter, we will cover accessible information on chemical kinetics, which is closely related to the subsequent discussion on MPs. For a more thorough and comprehensive understanding, we recommend referring to specialized monographs on chemical kinetics (such as “Chemical Biophysics: Quantitative analysis of Cellular Systems” by Beard & Qian [US])).