Bone is a highly adaptive material and is sensitive to disuse, immobilisation, surgical intervention, or activities involving high mechanical loads. Bone tissue may change its properties in response to changes in the biomechanical and biochemical environment. In this chapter, the cellular activities involved in bone remodelling, the theory of adaptive bone remodelling and the numerical frameworks developed in the last few decades to quantify this adaptive phenomenon have been discussed.

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Adaptive Bone Remodelling

  • Sanjay Gupta,
  • Ceby Mullakkara Saviour,
  • Bidyut Pal,
  • Souptick Chanda,
  • Kaushik Mukherjee

摘要

Bone is a highly adaptive material and is sensitive to disuse, immobilisation, surgical intervention, or activities involving high mechanical loads. Bone tissue may change its properties in response to changes in the biomechanical and biochemical environment. In this chapter, the cellular activities involved in bone remodelling, the theory of adaptive bone remodelling and the numerical frameworks developed in the last few decades to quantify this adaptive phenomenon have been discussed.