Health economics (HE) is a rapidly developing field in the health sciences. Health economics studies the rational use of limited resources in the healthcare industry. The United Arab Emirates’ (UAE) health economy has grown steadily; and academic knowledge and technical training have advanced in the public and private sectors. The UAE’s health economics professionals analyze and implement advanced economic evaluation models of healthcare interventions, improving the utilization of various resources in healthcare expenditure. This chapter examines the current health economics practice in the UAE. It explores the existing entities in this field of science in the UAE, including academic programs and scientific societies working in HE. This chapter provides insights into the challenges, opportunities, and features unique to UAE health economics. We aspire to explore the scope of the growing HE knowledge and identify facilitators and hurdles to advance the research and implementation of health economics in the UAE.