Correlation of Alzheimer’s Disease and Other Psychological and Non-Psychological Conditions

The primary cause of dementia in older people is Alzheimer’s disease (AD), which is typified by specific clinical and biochemical symptoms such as worsening memory loss and cognitive impairment. Furthermore, people with AD experience behavioural and psychological symptoms such as depression, apathy, aggression, and others, which will be explored in this chapter of the book. We will also discuss the clinical correlation between psychosis and AD. Recent research indicates a connection between sleep disturbances and AD. They are regarded as predictors of neurodegenerative disease. Long-term memory consolidation depends on sleep, and disturbances such as excessive daytime drowsiness and frequent awakenings may be early signs of AD. There are clinical links between AD and metabolic disorders. This chapter analyses the signs of osteoporosis and diabetes mellitus in an AD patient. Equally important is the link between AD and cardiovascular diseases such as atrial fibrillation and coronary heart disease, which can result in premature mortality. The association between older people’s gut microbiota and cognitive impairment will be discussed in this chapter. Older people’s microbiome structure maybe involved in controlling neuroinflammation, which is connected to various ageing-related neurological disorders, including AD.