The current scoping review covers 29 articles in five categories of Hong Kong university students’ developmental issues. These include 17 articles on depression, anxiety, and stress, 3 articles on non-suicidal self-injury, suicidal ideation, and suicidal behavior, 6 articles on addictive behavior, 7 articles on sleep problems and eating disorders, and 2 articles on physical assault and interpersonal violence, with some articles covering multiple issues. This chapter first analyzed the prevalence rates of Hong Kong university students’ developmental issues and compared them with studies based on other populations. Then, this chapter examined whether students’ holistic development, well-being, and quality of life were emphasized in the Institutional Learning Outcomes (ILOs) of 11 public and private institutions in Hong Kong. The results showed that Hong Kong university students had higher prevalence rates of non-suicidal self-injury, suicidal ideation and behavior, and physical assault perpetration against dating partners when compared to the international samples of college students. For ILOs, Hong Kong higher education institutions had a stronger emphasis on employment capability and cognitive skills, moderate emphasis on character and citizenship, and a minor emphasis on non-cognitive skills and interpersonal competence. These findings suggest that local higher education institutions may not adequately address students’ holistic development.