The development of intracardiac care systems has provided important medical support for patients with heart disease. However, traditional care methods have some limitations. This study aims to evaluate the effect of intelligent human–computer interaction technology in the intracardiac care system, and conducts research through questionnaire surveys and descriptive statistical analysis methods. Research results show that the application of intelligent human–computer interaction technology has a positive impact on the accuracy of nursing operations, patient safety, patient satisfaction and caregiver satisfaction. These research results provide an important reference for the improvement and optimization of the intracardiac care system, help to improve the quality and efficiency of care, and promote the satisfaction of patients and caregivers. The contribution of this study is to comprehensively evaluate the application effect of intelligent human–computer interaction technology in intracardiac care systems, and to provide guidance and inspiration for further research and practice.