With globalization and the rapid development of science and technology, intelligent media civilization has become an important feature of today’s society. As a form of media with high communication efficiency and coverage, short videos make it easier for people from different cultural backgrounds to understand and contact other cultures, thus promoting cross-cultural communication on a global scale. By analyzing the theory of cross-cultural communication and intelligent media technology, this study proposes a series of short video communication strategies, including in-depth understanding of the culture of the target market, improving the production level of short videos, focusing on content innovation and diversification, making full use of social media platforms, realizing cross-border cooperation and resource sharing, and applying intelligent algorithms for personalized recommendation and real-time monitoring. Meanwhile, this study highlights the importance of data-driven and intelligent analysis in optimizing the communication strategy of short videos, analyzing the communication effect through big data technology and predicting the future development trend of short videos in cross-cultural communication.