Climate change will likely increase nematode populations and disease risk, especially for plant-parasitic nematodes, due to rising temperatures and altered precipitation. Prediction models can forecast these changes by integrating climate data and nematode biology, aiding in developing management strategies. These models shall be useful for agriculture, but uncertainties remain due to data gaps and nematode adaptability. This chapter provides a comprehensive examination of developing prediction models for nematode pathogens under climate change, focusing on forecasting changes in nematode populations and disease risk to aid in effective management strategies. It builds on recent research and integrates findings from multiple studies to offer a detailed perspective for researchers, policymakers, and agricultural practitioners.