Chromium (Cr) and especially its hazardous form, hexavalent chromium (Cr6+), create a high-risk environmental and health hazard, which is very toxic, mobile, and persistent in the dangerous waste sites of industry. Traditional remediation methods, such as chemical precipitation and soil washing, often fail to achieve complete decontamination and produce secondary pollution. Plant-associated bacteria and fungi in the rhizosphere microbiome are responsible for chromate reduction, adsorption, and sequestration in this process. Scientists recently developed chromium-tolerant microbial consortia in microbial engineering with high bioremediation potential. These engineered consortia utilise synergistic interactions between the microbes in such consortia to improve Cr6+ reduction to the less toxic trivalent form of chromium (Cr3+), facilitate bioaccumulation, and promote a plant-microbe-assisted phytoremediation strategy. This chapter is dedicated to understanding how chromium-tolerant rhizosphere microbiomes can be crucial in bioremediation, microbiome diversity, metabolic interactions, and genetic adaptations. It further depicts engineered microbial consortia’s design and field implementation for effective chromium detoxification in industrially polluted environments. Using microbial consortia and integrating synthetic biology, bioinformatics, and nanotechnology is a promising direction for developing sustainable strategies for chromium remediation.