The microencapsulation of essential oils represents a promising approach to addressing challenges in the healing of chronic wounds. This study aims to elaborate high-performance biopolymer microcapsules and to fix them to gauze dressings for biomedical applications. The influence of various formulation and process parameters on the physical and functional properties of the microcapsules was investigated. These parameters included clay concentration, crosslinking agent concentration (calcium chloride (CaCl₂)), the molecular weight of sodium alginate, as well as stirring speed and duration. A kinetic study was conducted to evaluate the encapsulation efficiency and release profile of the essential oil within the microcapsules. Spectrophotometric analysis revealed that optimal encapsulation efficiency was achieved with a moderate clay concentration, medium molecular weight alginate, low CaCl₂ concentration, and gentle stirring for a short duration. The microcapsules were applied to gauze dressings using the exhaustion method with different types of binders. Synthetic binders, such as polyurethane and polyacrylic, as well as natural binders, including sodium alginate and chitosan, were tested. Morphological analysis of the fixed microcapsules was conducted to assess their distribution and integrity on the gauze dressings. The kinetic study demonstrated that the binder type plays a key role in the essential oil release profile. Notably, natural binders facilitated a rapid release, whereas synthetic binders resulted in a more sustained release. However, this study is limited by the absence of clinical trials, which would involve applying the dressings to patients to assess potential allergic reactions, irritations, or other adverse effects. These investigations will be the focus of a future study.