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Mass spectrometry imaging (MSI) is a two-dimensional mass spectrometry method for visualizing the spatial distribution of biomolecules (Fig. 28.1) [1]. Specifically, a thin section of a biological sample is ionized by two-dimensional scanning with an ion source such as a laser, and the generated ions are detected by a mass spectrometer. MSI can detect thousands of compounds from a single tissue section without extraction, purification, or separation.

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Mass Spectrometry Imaging (MSI)

  • 章节

  • 发表日期：

    2026年

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  • Ryo Omagari,
  • Naoki Koike,
  • Mitsutoshi Setou

摘要

Mass spectrometry imaging (MSI) is a two-dimensional mass spectrometry method for visualizing the spatial distribution of biomolecules (Fig. 28.1) [1]. Specifically, a thin section of a biological sample is ionized by two-dimensional scanning with an ion source such as a laser, and the generated ions are detected by a mass spectrometer. MSI can detect thousands of compounds from a single tissue section without extraction, purification, or separation.