The traditional hydraulic walking system of agricultural machinery is characterized by low efficiency and high emissions. By combining hydraulic technology with electronic information technology, an efficient and easily controllable electro-hydraulic load sensing system is proposed. A system simulation model was established, and the simulation results were analyzed. The results indicate that the electro-hydraulic load-sensitive walking hydraulic control system in pure electric-driven agricultural machinery can detect the maximum load pressure through pressure sensors and provide feedback to the controller. The controller outputs a speed signal to adjust the speed of the permanent magnet synchronous motor and dynamically adjusts the outlet flow of the quantitative pump. The system adopts a closed-loop control with a preset variable pressure difference, so that the pump outlet pressure follows the change of the maximum load pressure. When the load of the hydraulic motor suddenly changes, the system adjusts the opening of the electromagnetic proportional valve via the controller to ensure that the speeds of the left and right walking hydraulic motors are the same. Therefore, agricultural machinery can automatically travel in a straight line. In conclusion, the electro-hydraulic load-sensitive walking hydraulic control system improves the load adaptability of pure electric agricultural machinery.