Chiral thioethers are a fascinating class of organic compounds that contain sulfur atoms bonded to two different carbon atoms, commonly represented as R–S–R’. These molecules become chiral when one of the connected carbon atoms forms an asymmetric center, and they are organosulfur compounds within organic chemistry [1]. Chirality refers to the property of a molecule that allows it to exist as two nonsuperimposable mirror images, known as enantiomers, which behave like left and right hands [2]. This slight difference between enantiomers has a profound impact on their physical and chemical properties, making chiral thioethers important in various fields, including pharmaceuticals, catalysis, and materials science [3–5]. The study of organosulfur compounds, including chiral thioethers, has a long history dating back to the early days of organic chemistry, with significant research focused on their properties, synthesis, and uses [6]. For example, some compounds have exhibited spontaneous chiral crystallization, highlighting the influence of sulfur on the phenomenon of chirality [7]. Over time, the versatility of chiral thioethers has made them key targets for study in both academic research and industrial applications [8].

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Introduction

  • Qingle Zeng,
  • Muhammad Khuzaifa

摘要

Chiral thioethers are a fascinating class of organic compounds that contain sulfur atoms bonded to two different carbon atoms, commonly represented as R–S–R’. These molecules become chiral when one of the connected carbon atoms forms an asymmetric center, and they are organosulfur compounds within organic chemistry [1]. Chirality refers to the property of a molecule that allows it to exist as two nonsuperimposable mirror images, known as enantiomers, which behave like left and right hands [2]. This slight difference between enantiomers has a profound impact on their physical and chemical properties, making chiral thioethers important in various fields, including pharmaceuticals, catalysis, and materials science [3–5]. The study of organosulfur compounds, including chiral thioethers, has a long history dating back to the early days of organic chemistry, with significant research focused on their properties, synthesis, and uses [6]. For example, some compounds have exhibited spontaneous chiral crystallization, highlighting the influence of sulfur on the phenomenon of chirality [7]. Over time, the versatility of chiral thioethers has made them key targets for study in both academic research and industrial applications [8].