Scholarlink

Non-cardiac chest pain (NCCP) is epidemiologically common among cases of chest pain, and most causes of NCCP originate from esophageal disorders within the spectrum of gastrointestinal diseases. Among these, functional esophageal disorders hold an important clinical position, with key symptoms including heartburn, chest pain, and dysphagia. These disorders involve overlapping conditions such as esophageal motility disordersEsophageal motility disorders, gastroesophageal reflux disease (GERD)Gastroesophageal reflux disease (GERD), and NCCP. For diagnosis, it is essential first to rule out structural diseases of the upper gastrointestinal tract and ischemic heart disease. Subsequently, diagnostic tests such as esophagography, esophageal manometry, and 24-hour esophageal impedance-pH monitoring24-hour esophageal impedance-pH monitoring are necessary. The mechanism of pain in NCCP is thought to involve a lowered pain threshold. Emotional stress, such as anxiety, and psychosocial factors also contribute to the condition, often leading to delays in diagnosis and treatment. Therefore, while appropriate pharmacological treatment tailored to each individual pathology is essential, a psychosomatic approach similar to that used in treating functional somatic syndromes and chronic pain is also recommended.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Diagnosis and Treatment of Motility Disorder of the Esophagus, Non-Cardiac Chest Pain

  • 章节

  • 发表日期：

    2026年

查看全文
  • Yasushi Funaki,
  • Naotaka Ogasawara,
  • Kunio Kasugai

摘要

Non-cardiac chest pain (NCCP) is epidemiologically common among cases of chest pain, and most causes of NCCP originate from esophageal disorders within the spectrum of gastrointestinal diseases. Among these, functional esophageal disorders hold an important clinical position, with key symptoms including heartburn, chest pain, and dysphagia. These disorders involve overlapping conditions such as esophageal motility disordersEsophageal motility disorders, gastroesophageal reflux disease (GERD)Gastroesophageal reflux disease (GERD), and NCCP. For diagnosis, it is essential first to rule out structural diseases of the upper gastrointestinal tract and ischemic heart disease. Subsequently, diagnostic tests such as esophagography, esophageal manometry, and 24-hour esophageal impedance-pH monitoring24-hour esophageal impedance-pH monitoring are necessary. The mechanism of pain in NCCP is thought to involve a lowered pain threshold. Emotional stress, such as anxiety, and psychosocial factors also contribute to the condition, often leading to delays in diagnosis and treatment. Therefore, while appropriate pharmacological treatment tailored to each individual pathology is essential, a psychosomatic approach similar to that used in treating functional somatic syndromes and chronic pain is also recommended.