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Alpine medicinal plants grow in high-altitude conditions such as extreme cold, strong UV radiation, limited nutrients, and short growing seasons. To survive these harsh conditions, they have evolved unique physiological traits, including the production of diverse secondary metabolites with strong medicinal potential. This chapter summarizes current knowledge on alpine plant ecology, traditional uses, and phytochemical diversity, emphasizing how multi-omics approaches are advancing this field. Genomic, transcriptomic, proteomic, metabolomic, epigenomic and microbiome studies reveal how genes, enzymes and microbes work together to enhance stress tolerance and metabolite production. Integrating these datasets through systems biology and machine learning helps identify key regulatory networks and pathways for metabolic engineering and conservation.

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Plant Omics and Co-expression Networks Capture Key Components of Secondary Metabolites Biosynthesis in Alpine Medicinal Herbs

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  • 发表日期：

    2026年

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  • Bhawna Kumari,
  • Rutvik Sameer Kulkarni,
  • Siddhant Diliprao Mahabale,
  • Rashmi Kishor Agashe,
  • Varun Kumar,
  • Rajinder Singh Chauhan

摘要

Alpine medicinal plants grow in high-altitude conditions such as extreme cold, strong UV radiation, limited nutrients, and short growing seasons. To survive these harsh conditions, they have evolved unique physiological traits, including the production of diverse secondary metabolites with strong medicinal potential. This chapter summarizes current knowledge on alpine plant ecology, traditional uses, and phytochemical diversity, emphasizing how multi-omics approaches are advancing this field. Genomic, transcriptomic, proteomic, metabolomic, epigenomic and microbiome studies reveal how genes, enzymes and microbes work together to enhance stress tolerance and metabolite production. Integrating these datasets through systems biology and machine learning helps identify key regulatory networks and pathways for metabolic engineering and conservation.