The human-nature connection is critical for sustaining ecological conservation, since people’s ability to access and interact with nature can promote ecological stewardship. However, urbanisation has become a major threat to ecological integrity in many cities, including the Western Parkland City in the Greater Sydney Area. This loss of human-nature interaction can hinder effective ecological conservation and accelerate environmental degradation. Orchard Hills, a priority precinct in the Greater Penrith to Eastern Creek area, is expected to anticipate significant growth with the new Metro station. This offers an opportunity to adopt an ecocentric approach, aiming to protect and enhance existing ecosystems while still accommodating growth. However, this opportunity also poses a threat to the existing riparian ecosystem near Wianamatta South Creek. Therefore, this study aims to develop urban design recommendations that foster human-nature connections within the precinct, utilising an ecocentric urbanism approach. This study employs a design practice-led research methodology, drawing on contemporary urban design literature to establish a theoretical framework based on Biodiversity Sensitive Urban Design (BSUD), Nature-based Solutions (NbS), and Nature-Driven Urbanism (NDU). This study finds that applying NDU in the early design process can optimally ensure landscape resilience by identifying vulnerabilities and key ecosystems for protection. Subsequently, implementing NbS as a foundational strategy for designing green and blue infrastructure can strengthen ecosystem resilience. BSUD provides a valuable methodology for designing habitats tailored to specific species. This research thus offers insights into an ecological approach for master planning a new precinct around a transit station. It suggests that a thoughtfully integrated ecocentric design can balance urban development with environmental resilience by supporting biodiversity, enhancing ecological connectivity, and fostering meaningful human-nature interactions.