Vibrio spp. represents a group of common bacteria characterized by their curved rod or comma like shape and Gram-negative nature. They are naturally found in various aquatic environments, including freshwater, estuaries, and the vast expanses of the sea. These bacteria play a pivotal role in a spectrum of infections collectively referred to as vibriosis. The severity of these infections can span a wide range, from mild ailments to life-threatening conditions. Marine environments serve as the favored habitat for Vibrio bacteria, and infections often arise from contact with contaminated water or the consumption of contaminated seafood. Although over a 100 distinct Vibrio species have been described, it is a selected group of approximately 12 that cause infections in humans. Vibrio cholerae, a notable member of this bacterial family, is responsible for the devastating disease cholera. Several non-cholera Vibrio spp. orchestrate onset of disease recognize as “Vibriosis”. Some species, such as V. cholerae non-O1 and V. mimicus, have demonstrated the ability to adapt and survive in freshwater environments. In addition to their adaptability, there are halophilic vibrios, which are specifically adapted to saline environments. The sodium dependence is a key characteristic of halophilic vibrios, reflecting their specialization for salt-rich environments.