This chapter discusses the adaptation of Jeff VanderMeer’s Annihilation, directed by Alex Garland, and regards how a novel that is linguistically impossible to adapt was translated into a visual medium while maintaining the essence of ecological emphasis. It investigates the writing and directorial decisions made by Alex Garland to evoke the environmental visuals and the spirit of the narrative while utilizing visual inspiration, such as the sci-fi films Roadside Picnic and Alien, to create something new. The film creates origins and answers for the pseudo-antagonist of the work, compared to the open-ended novel which plays out without the inspection—or expectation—of answers to what can only remain unknown to humanity. This chapter considers the difference Garland introduced in making the film more of an alien invasion feature compared to the ecological investigation of nature’s reclamation of humanity dealt with in the novel. Reflecting on the auteur’s gaze regarding speculative fiction, this is an analysis of the changes made by Garland, keeping in mind the question: “What can you do when the five senses are not enough?”