Young farmers are often more adaptive to advances in science and technology, so they are more familiar with digital devices and modern agricultural practices. In agricultural product marketing activities, digital technology provides enormous opportunities for farmers and business actors to reach a wider market and increase efficiency. This study examines the effect of e-commerce and social media literacy on increasing agricultural product sales and the role of digital literacy and consumer responses on social media as moderating variables in increasing agricultural product sales. This research is a quantitative descriptive study based on primary data. Sleman Regency was chosen as the research location because, in this area, there is an active millennial farmer institution to develop “agrosociopreneurship.” The sample determination used a purposive method, namely selecting young farmers who had been members of “Petani Millennial Sleman” for over a year and were familiar with e-commerce and social media platforms. The analysis in this study used PLS-SEM. The results showed that e-commerce literacy and product branding through social media significantly increased agricultural product sales. Consumer responses on social media can strengthen the influence of product branding on increasing agricultural product sales. In contrast, digital literacy does not moderate the impact of e-commerce literacy or product branding through social media on growing sales of farm products.