Natural bioactives derived from marine sources have become a promising area of neuroscience research, providing creative and beneficial scientific approaches to movement disorders. These disorders, which include essential tremor, dystonia, and Parkinson’s disease, frequently have intricate pathophysiological underpinnings that make modern treatment strategies difficult to implement. Numerous distinct bioactive substances with neuroprotective, anti-inflammatory, and antioxidative qualities are produced by marine species, including algae, sponges, mollusks, and marine microorganisms. This chapter examines how these marine bioactives may alter important molecular pathways, such as neurotransmitter modulation, mitochondrial function, and neuroinflammation, that are implicated in movement disorders. The chapter emphasizes the increasing significance of marine natural products as therapeutic and preventive agents by combining knowledge from marine pharmacology, neurobiology, and therapeutic development. This strategy’s interdisciplinary nature provides a fresh foundation for future studies and medication development targeted at reducing the burden of neurological disorders linked to movement.