Scholarlink

In order to assess the effects of long-term exposure to low-dose-rate radiation in the crystalline lens, eyes of 114 wild Japanese macaques inhabiting the vicinity of Fukushima Daiichi Nuclear Power Plant (FNPP) were examined 3–11.4 years after the accident that caused a massive release of radioactive materials in 2011. Histological examinations revealed dissection of the superficial cortex along the Y-shaped sutures (water cleft) and the presence of vacuoles, typical of early-stage cataracts. Unlike diabetic cataract rats, aquaporin 0 (AQP0) and AQP5 did not accumulate around these vacuoles, suggesting that the cataracts observed in this study arise from a mechanism distinct from diabetic cataracts. Internal doses and dose rates were higher in the group with cataractous changes in the lens than in the group without such changes. However, it should be noted that these changes do not immediately lead to visual impairment or the development of cataracts. Despite the limitations inherent in fieldwork, the findings in this study contribute insights into the impact of cumulative low-dose-rate radiation on the lens and underscore the need for continued vigilance to protect both wildlife and humans from radiation-induced injury.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Effects of Low-Dose Radiation Exposure on the Crystalline Lens of the Japanese Macaque Eye

  • 章节

  • 出版模式：

    开放获取

  • 发表日期：

    2026年

查看全文
  • Naoki Yamamoto,
  • Noriko Hiramatsu,
  • Yu Kato,
  • Yumika Kuno,
  • Kana Aihara,
  • Natsuko Hatsusaka,
  • Hiroshi Sasaki,
  • Noriaki Nagai,
  • Yosuke Nakazawa,
  • Masatoshi Suzuki,
  • Manabu Fukumoto

摘要

In order to assess the effects of long-term exposure to low-dose-rate radiation in the crystalline lens, eyes of 114 wild Japanese macaques inhabiting the vicinity of Fukushima Daiichi Nuclear Power Plant (FNPP) were examined 3–11.4 years after the accident that caused a massive release of radioactive materials in 2011. Histological examinations revealed dissection of the superficial cortex along the Y-shaped sutures (water cleft) and the presence of vacuoles, typical of early-stage cataracts. Unlike diabetic cataract rats, aquaporin 0 (AQP0) and AQP5 did not accumulate around these vacuoles, suggesting that the cataracts observed in this study arise from a mechanism distinct from diabetic cataracts. Internal doses and dose rates were higher in the group with cataractous changes in the lens than in the group without such changes. However, it should be noted that these changes do not immediately lead to visual impairment or the development of cataracts. Despite the limitations inherent in fieldwork, the findings in this study contribute insights into the impact of cumulative low-dose-rate radiation on the lens and underscore the need for continued vigilance to protect both wildlife and humans from radiation-induced injury.