Saccharides play important roles in biological phenomena, as bioligands. However, the molecular recognition ability of saccharide is generally weak. It is known that the molecular recognition ability of saccharides is amplified by the cluster glycoside effects. Glycopolymers, which have saccharides on their side chains, are examples of molecules that effectively exhibit the cluster glycoside effect Since glycopolymers are large molecules, they exhibit effective molecular recognition ability. In addition, glycopolymers are polymers, they also function as biomaterials. This section provides an overview of methods for synthesizing glycopolymers, the development of precision synthesis, and their applications.