Recent advancements in the construction industry have influenced many aspects of human life, like in terms of economic feasibility, structural safety, and the fast pacing of construction activities. Historically, metal structures played a Important role during the early 20th century, notably aiding in infrastructure development throughout the Industrial Revolution and the challenges of World War II. In the present-day structural engineering, Pre-Engineered Buildings (PEBs) have emerged as a modern and efficient alternative to Conventional Steel Buildings (CSBs), giving solution to several limitations that arises with traditional construction techniques. Typically, industrial buildings may be classified into two structural categories: (1) structures with short spans employing continuous or cantilevered girders over columns, and (2) longer-span steel-framed industrial buildings supported by columns. In the present study, a comparative analysis between PEB and CSB systems is conducted for an industrial warehouse using STAAD.Pro. Main indicators such as base shear, storey drift, and the influence on structural stability were observed. The objective was to determine the optimal structural configuration under varying seismic and wind loading cases. Both structural models were analyzed and designed according to Indian Standards, IS 1893 for seismic loading and IS 875 Part 3 (2015) for wind load data.