This contribution examines the concept, significance, and spatial dimension of urban voids, defined as land plots resulting from abandonment, or abrupt change in use. Urban voids acquire meaning through their relationships with surrounding structures, symbolic values, and social functions. The notion of void extends beyond simple emptiness, incorporating relational and topological dimensions—where ‘interspaces’ become mediums for urban connectivity and scalar transition from architectural to landscape levels. Philosophical perspectives frame voids as both substance and relational space, highlighting their role in shaping human perceptions, dwellings, and spatial organization of cities. With this perspective in mind, voids became places of potential interaction, visual connection, and functional articulation within metropolitan landscapes. Architectural examples, such as squares and streets, illustrate diversified functions. Markets, gardens, and celebratory squares, for instance, serve commerce, social interactions, and symbolic representation, reflecting historical and contemporary urban practices. Pedestrianization of streets further demonstrates the functional adaptation of voids, improving neighborhoods’ quality, fostering human-scale experiences, and linking pedestrian systems with public transport. Based on these premises, our work underscores the interplay between form, function, and perception of urban voids, emphasizing their role as connective, dynamic spaces that (i) structure the city, (ii) mediate social interaction, and (iii) integrate multiple scales from micro-architecture to metropolitan (and landscape) levels. By integrating philosophical, architectural, and spatial planning perspectives, urban voids are framed as essential components of sustainable, human-centered metropolitan development.