Lot Fourteen is a powerful drama of urban renewal, as the forces of the past collide with the energy of emerging economies. This sector, which is situated on the site of the former Royal Adelaide Hospital, is neither a remote tech park on the outskirts nor a brand-new suburban campus (Cunningham and McCutcheon 2023). A central city redevelopment project that rewires Adelaide’s very center for the twenty-first century is something far more ambitious. Adelaide is establishing itself as a globally significant player in the knowledge economy by cultivating a network of enterprises in artificial intelligence, space technology, defence innovation, and creative industries within the walls of its old sandstone building.