Tyrosine Kinase Inhibitors
摘要
Deucravacitinib is a first-class, highly selective, oral tyrosine kinase 2 (TYK2) inhibitor, that is approved by the US-FDA for the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy/phototherapy. It represents a significant advancement in the treatment of psoriasis and related inflammatory conditions, offering a unique mechanism of action, robust efficacy and a favourable safety profile.