Famciclovir is the diacetyl ester prodrug of 6-deoxy penciclovir. In order to exhibit its antiviral effects, famciclovir needs to be converted to penciclovir (that takes place following first-pass metabolism in the liver). The indications of famciclovir are similar to acyclovir and valaciclovir. Its safety profile also simulates acyclovir and valacyclovir.

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Famciclovir

  • Aditya Kumar Bubna

摘要

Famciclovir is the diacetyl ester prodrug of 6-deoxy penciclovir. In order to exhibit its antiviral effects, famciclovir needs to be converted to penciclovir (that takes place following first-pass metabolism in the liver). The indications of famciclovir are similar to acyclovir and valaciclovir. Its safety profile also simulates acyclovir and valacyclovir.