In this study, the role of anode particle geometry on the internal short circuit (ISC) behavior of a lithium-ion cell is investigated through numerical simulations. A pseudo-two-dimensional (P2D) electrochemical model is implemented to systematically analyze the role of particle shape in governing the ISC characteristics. Anode microstructures comprising spherical, flake-shaped, and cylindrical particles are considered to assess the impact of geometrical distribution and variation on the ISC response of the cell. It is revealed that an anode with spherical particle distribution gives more generated capacity compared to cylindrical and flake particles. Further, cell voltage and internal short circuit current are found to be higher when an anode with spherical particles is used among all configurations investigated. Based on the results, an anode with flake particle geometry may help to reduce ISC current and mitigate immediate short circuit risks.