Routine and special histochemical stains in ocular pathology hold special status. Special stains for detecting microorganisms specially fungus, bacteria, acid fast bacillus, spirochetes etc. Various corneal dystrophies require special stains. Metallic deposition in ocular tissues can be seen by various special stains. Calcium, collagen, lipid, amyloid and many others require these specialized stains to demarcate the pathologies.