With the rapid development of the nuclear energy industry, the total amount of radioactive solid waste generated by the decommissioning of nuclear power plants and nuclear facilities in my country is increasing year by year, and the demand for the disposal of various types of radioactive solid waste is growing. In this context, it has become very necessary and urgent to conduct systematic and in-depth research on the technical and economic data of medium-depth and deep geological radioactive solid waste repositories. This paper studies the life-cycle cost data of medium-depth and deep geological disposal radioactive solid waste repositories at home and abroad, gives the life-cycle unit disposal cost range of medium-depth and deep geological repositories, and identifies the main parameters that affect cost calculation. Life cycle cost prediction method provides cost reference for program selection and economic evaluation of subsequent projects.