The South African hospitality industry faces substantial challenges, including economic fluctuations, climate change, and shifting consumer preferences. To navigate these issues effectively, adopting both resilience and regenerative strategies is crucial. Resilience theory advocates for developing robust crisis management plans, diversifying income sources, and building strong community relationships to help hotels recover from disruptions. Key adaptation strategies include flexible operational practices, such as adaptive staffing and resource management, as well as staff training programs that enhance adaptability and operational efficiency. The integration of technology, such as digital tools for real-time monitoring and data analysis, also plays a significant role in improving crisis management and operational flexibility. Service-dominant logic (SDL) highlights the significance of engaging guests in sustainable practices, enhancing guest satisfaction, and fostering environmental stewardship. Ecological modernisation theory supports the implementation of renewable energy and other regenerative practices, aligning with SDG 7 (Affordable and clean energy) and SDG 12 (Responsible consumption and production). This study employed a qualitative approach, incorporating in-depth semi-structured interviews with hotel managers and a comprehensive literature review, with data analysed through thematic coding. Key findings indicate that effective resilience strategies involve creating robust crisis management frameworks, diversifying revenue streams, and nurturing community ties. Regenerative adaptations focus on supporting local biodiversity, reducing waste, and implementing renewable energy solutions. A significant emphasis is placed on educating guests about sustainability, which is vital for improving operational efficiency and enhancing guest awareness. Recommendations include addressing research limitations, exploring long-term adaptation strategies, and integrating emerging technologies like AI and blockchain. Integrating resilience and regenerative practices is essential for ensuring the long-term sustainability of South Africa’s hospitality sector and advancing global sustainability goals.