Herpes simplex and Herpes zoster viruses are the common causes of viral keratitis with variable clinical presentation. The treatment options for viral keratitis primarily include antivirals and steroids. Researchers have done various studies to understand the rationale of these two drugs tailored to the clinical presentation of viral keratitis. This chapter provides a detailed description of the landmark trial, herpetic eye disease study (HEDS), and an overview of the Zoster Eye Disease Study (ZEDS).

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Clinical Trials in Viral Keratitis

  • Pranita Sahay,
  • Kanchita Pandey,
  • Prafulla Maharana,
  • Brindha Periasamy

摘要

Herpes simplex and Herpes zoster viruses are the common causes of viral keratitis with variable clinical presentation. The treatment options for viral keratitis primarily include antivirals and steroids. Researchers have done various studies to understand the rationale of these two drugs tailored to the clinical presentation of viral keratitis. This chapter provides a detailed description of the landmark trial, herpetic eye disease study (HEDS), and an overview of the Zoster Eye Disease Study (ZEDS).