Radon-222 isotope is one of the stable isotopes that has a half-life of 3.82 days and causes many studies that utilize its decay period for research in various fields and one of them is in the scope of groundwater. In a negative perspective, excessive 222Rn content can also have an impact on human health. In a contradictory, the use of 222Rn in water aims to obtain an information related to the groundwater quality, groundwater system, and other related topics. The presence of 222Rn in water is influenced by various factors in rocks, such as characteristics, permeability, and mineral content. Indirectly, the process of studying groundwater potential involves factors that are quite similar to 222Rn concentration availability in water, such as rock permeability and porosity, to determine the groundwater potential in a groundwater basin. The similarity of the influencing factors between the availability of 222Rn in water and groundwater potential in an area encourages research activities to understand the process and relationship between the two. The methods planned for research activities are divided into 4 main outlines: field mapping, water sampling, 222Rn content testing in water, and approaching of analysis using a remote sensing. The research that will be conducted will be focused on locations with volcanic geological settings. The research aims to utilize the content of 222Rn in water from a different perspective to study the relationship and possibility of the presence of 222Rn, especially related to groundwater potential in an area with a remote sensing approach.