A low voltage low power multiple output operational transconductance amplifier circuit using a bulk-driven technique (MO-OTA) is presented in this chapter. The proposed realization powered at ±0.6 V with a reduced power consumption of 32.29 \(\upmu \) W shows a wide linear input range, very low \(G_m\) value 26.33 \(\upmu S\) and high open loop gain of 62.63 dB with transition frequency at 4 MHz. To verify the proposed concept, a post-layout simulation of proposed circuit has been performed. It occupies a small effective area of 31.17 \(\upmu \) m \(\times \) 48.36 \(\upmu \) m. Based on this circuit, two applications are described. In the first one, a second Gm-C filter based on using five OTAs circuits with three capacitors is implemented. In the second application, a new current mode bi-quadratic filter (SIMO) possessed by three multi-output OTAs and two capacitors is realized. It can achieve all the standard filter functions. The simulation results of these filters are in a good accuracy with the theoretical calculations. All simulations are performed by Cadence technology CMOS 0.18 \(\upmu \) m.